A pathway to new medicines: Aarhus University and the pharma industry join forces
Aarhus University and several pharmaceutical companies – both Danish and foreign – are joining forces in the Open Discovery Innovation Network (ODIN), a groundbreaking open research collaboration whose ambition is to create long-term innovation to benefit patients, industry and society.
ODIN explained
The basic idea behind the ODIN is to improve the ability to convert research results into new products and solutions. ODIN is a pilot project that will be a free space for the next three years. Without the restrictive framework of patents, ODIN will boost and use the collective thinking and creativity of the participating university researchers and nine pharmaceutical and biotech companies, enabling them to refine ideas and accelerate projects. The project is based on a concept that Aarhus University has developed over several years.
I am delighted that an environment is being established at Aarhus University that can tap into the strong competencies in pharmaceutical development of the university and industry. The pilot project is based on close collaboration between basic research and many companies in the first small steps towards developing new medicine. Another great potential for the project is that it can be expanded to other areas such as green tech and thus be a role model for new partnerships between research and industry.
Mutual benefits
The overall ambition is to create accelerated and more effective discovery of new pharmaceuticals by having a strong foundation of basic knowledge and analytical tools that everyone can access – including competing companies. Pharmaceutical companies use many resources in patenting new drugs, but they need many of the same analytical tools and knowledge for the earliest stages of product development. That is why collaboration is attractive.
This initiative is especially interesting, since it links different forms of collaboration and creates a platform that will increase the opportunities for building bridges between industry and academia. This will create entirely new synergy opportunities for the life sciences in Denmark, and we expect it to be a win–win model for the pharmaceutical industry, biotech and academia,
University researchers receive access to companies’ know-how and automation expertise – and several companies, for example, have made their own screening libraries and molecules available, which can boost and accelerate researchers’ work.
The ODIN network currently comprises researchers from the natural, technical and health sciences faculties at Aarhus University as well as industry partners, including Novo Nordisk A/S, LEO Pharma A/S, H. Lundbeck A/S, Boehringer Ingelheim and Nordic Bioscience. Other companies and researchers are welcome to participate in the project.
A university lives by sharing knowledge and good ideas, and ODIN’s open format provides the basis for both researchers and companies to do just that. I am therefore sure that ODIN will benefit the participants – and ultimately Denmark. This is a key part of Aarhus University’s strategy that we want to strengthen collaboration between research and business, and our experience with open science suggests that this is a good model that can greatly benefit both parties.
ODIN - a first of its kind in Denmark
The ODIN collaboration will make it easy for researchers and companies to create the building blocks that are important for developing future medicines – for example, developing new platforms and techniques for testing the specificity and unintended effects of medicine – which do not have much commercial value by themselves. Although ODIN’s open results cannot be patented, everyone is free to customize and, based on that, develop products that can be commercially protected.
According to Rasmus Beedholm-Ebsen, Special Advisor Life Sciences at Invest in Denmark, and located in Aarhus, the Open Discovery Innovation Network is a testament of the close interplay between public and private partners across science, education and regulatory affairs present in Denmark. Aarhus University has a long tradition for both interdisciplinary and industry collaboration. Rasmus Beedholm-Ebsen is therefore not surprised that such a collaboration as ODIN, which is the first of this type in Denmark, originates from Aarhus University.
Experiences from initiatives abroad, such as the Structural Genomics Consortium in Oxford, indicate great potential for such projects.
All participants are free to offer solutions or ideas to qualify projects. Participation is voluntary, so only projects that appeal to both parties take off. Once this happens, the grant from the Foundation will fund research capacity in the form of employing postdoctoral fellows, PhD students and others.
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